217582
Nefazodone Hydrochloride (5-HT2A Serotonin Receptor Antagonist, Nefazodone, BMY-13754, MJ-13754-1, Serzone)
Size
£416.00
- SKU:
- 217582
- Molecular Weight:
- 470.01
- Purity:
- ≥99% (HPLC)
- Storage Conditions:
- 4°C
- Supplier:
- United States Biological
- CAS Number:
- 82752-99-6
- Format:
- Supplied as a white solid.
- Extra Details:
- A potent 5-HT2A receptor antagonist (Kd = 26nM), with moderate affinity for the alpha1-adrenergic receptor (Kd = 48nM) and 5-HT1A receptor (Kd = 80nM). Originally developed as a clinical antidepressant but discontinued in 2004, nefazodone (Serzone) still remains a specific inhibitor of certain serotonergic pathways. Nefazodone also has been reported to induce mitochondrial dysfunction. CAS Number: 82752-99-6 Solubility: DMSO or EtOH Primary Target: 5-HT2A Primary Target Ki: 26nM Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice