MPEP Hydrochloride (6-Methyl-2-(phenylethynyl)pyridine Hydrochloride)

Size

£429.00

SKU:: 217564
Purity:: ~99% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 96206-92-7
Format:: Supplied as a white solid.
Extra Details:: A non-competitive, highly potent antagonist selective for mGlu5 receptors (IC50 = 36nM). Also a positive allosteric modulator of mGlu4 and weak anatagonist of nMDA receptors. Biologically active admitted systematically. Widely used in assessing the functional roles of mGlu5 receptors in a variety of research areas, such as learning and memory, sleep, neuroprotection, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinson's disease. CAS Number: 96206-92-7 Formula: C14H11N Å• HCl Solubility: DMSO Primary Target: mGlu5 receptors Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.