L-741,626 (Dopamine D2 Receptor Antagonist, L-741,626, L-741626, L741626)

Size

£350.00

SKU:: 217501
Purity:: ≥99% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 81226-60-0
Format:: Supplied as a white solid.
Extra Details:: Selective dopamine D2 receptor antagonist that is shown to reversibly block agonist-induced activation of GIRK currents. Reported to have a 15-fold selectivity for D2R over D3R in vitro. Inhibition of 3H-spirperone binding to cloned rat Dopamine receptors show the following Ki values: D2R (7.1nM), D3R (155nM), D4R (596nM). Commonly used D2 inhibitor in addiction research. CAS No: 81226-60-0 Molecular Formula: C₂₀H₂₁ClN₂O Solubility: DMSO Primary Target: D2 Primary Target Ki: 7.1nM Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.