L-701,324 (7-Chloro-4-hydroxy-3-(3-phenoxy)phenyl-2(1H)-quinolinone)

Size

£408.00

SKU:: 217500
Purity:: ~98% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 142326-59-8
Format:: Supplied as a white powder.
Extra Details:: A highly potent and selective antagonist for thenMDA receptor glycine site (IC50 = 2.0nM; Kd = 28nM; ED50 = 0.9nM either intraperitoneal (ip) or oral (po) adminited). The first such compounds with significant activity in the central nervous system following oral dosing and a potent, active anticonvulsant with a reduced propensity to activate mesolimbic dopaminergic systems in rodents. CAS Number: 142326-59-8 Formula: C21H14CINO3 Solubility: DMSO Primary Target: NMDA receptors Primary Target IC50: 2.0nM Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.