217484
JNJ 16259685
Size
£358.00
- SKU:
- 217484
- Molecular Weight:
- 325.41
- Purity:
- ≥98% (HPLC)
- Storage Conditions:
- 4°C
- Supplier:
- United States Biological
- CAS Number:
- 409345-29-5
- Format:
- Supplied as a white solid.
- Extra Details:
- An extremely potent, non-competitive antagonist for mGlu receptor subtype 1 (Ki = 0.34nM; IC50 = 0.55nM). 400-fold more selective for mGlu1 than for mGlu5 and no interaction with mGlu2, mGlu3, mGlu4, mGlu6, AMPA ornMDA receptors (IC50 >10uM). Centrally active following systemic administration. Widely used for studying substance abuse, learning and memory, and neural plasticity. Synonyms: (3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl)-methanone CAS Number: 409345-29-5 Molecular Formula: C₂₀H₂₃NO₃ Molecular Weight: 325.41 Primary Target: mGlu1 Primary Target IC50: 0.55nM Primary Target Ki: 0.34nM Solubility: DMSO Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice