Eliprodil (alpha-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, NMDA Antagonist IX)

Size

£345.00

SKU:: 217339
Molecular Weight:: 347.86
Purity:: ~99% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 119431-25-3
Format:: Supplied as a white solid.
Extra Details:: A negative allosteric modulator selective for NR2B containingnMDA receptors (IC50 = 1, >100, and >100uM for NR2B, NR2A, and NR2C, respectively). Also a potent ligand for alpha1 receptor (Ki = 0.013uM), one of the two types of unique non-opioid, non-phencyclidine brain alpha receptors. Blocks neuronal voltage-gated Ca2+. CAS Number: 119431-25-3 Formula: C20H23ClFNO Solubility: DMSO Primary Target: NMDA receptors Primary Target IC50: 1, > 100, and > 100 →M for NR2B, NR2A, and NR2C, respectively. Molar Mass: 347.86 Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.