CNQX (6-Cyano-7-nitroquinoxaline-2,3-dione, 6-Cyano-2,3-dihydroxy-7-nitro-quinoxaline)

Size

£366.00

SKU:: 217278
Purity:: ~99% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 115066-14-3
Format:: Supplied as a cream solid.
Extra Details:: A potent and competitive antagonist for AMPA/kainate receptors (Ki = 0.6-2.11uM for GluA1-4 and Ki = 1.3-5.3uM for different subtypes of Kainate receptors) and a negative allosteric modulator atnMDA receptor glycine binding site. Widely used for assessing the functional roles of neurotransmission mediated by glutamate receptors in both normal and abnormal brain functions. CAS Number: 115066-14-3 Formula: C9H4N4O4 Solubility: DMSO Primary Target: AMPA Primary Target Ki: 0.6-2.11 →M for GluA1 - 4 and Ki Secondary Target: Kainate Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.