Bupropion Hydrochloride (Dopamine and Noradrenalin Transporter Inibitor, Bupropion)

Size

£403.00

SKU:: 217232
Purity:: ≥99% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 31677-93-7
Format:: Supplied as a white solid.
Extra Details:: A non-selective inhibitor of dopamine and noradrenalin transporters (Ki = 1.4, 2.8 and 45uM for dopamine, noradrenalin, and serotonin transporters respectively). Also an antagonist for neuronal nicotinic acetylcholine receptors (nAChrs) (IC50 = 1.8uM at alpha2beta2 receptor). Clinically used as an antidepressant and smoking cessation drug. Used in nicotinic addiction and depression studies. CAS Number: 31677-93-7 Molecular Formula: C₁₃H₁₈ClNO·HCl Solubility: H2O Primary Target: DAT/NET Primary Target Ki: 1.4u Storage and Stability: May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.