Adenosine A2A Receptor Antagonist II, SCH-58261 (2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, SCH58261, SCH 58261)

Size

£563.00

SKU:: 217152
Purity:: ≥99% (HPLC)
Storage Conditions:: 4°C
Supplier:: United States Biological
CAS Number:: 160098-96-4
Format:: Supplied as an off-white solid.
Extra Details:: A highly potent and selective antagonist of adenosine A2A receptor (Ki = 600pM). Does not affect the activity of other adenosine receptors in any significant manner (Ki = 287nM; 5uM, and > 10uM for A1, A2B, and A3 receptors, respectively). Displays neuroprotective effects in cerebral ischaemia in rats, and shown to counteract Parkinsonian-like muscle rigidity in rats. Synonyms: 2-(furan-2-yl)-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine, SCH58261, SCH 58261 CAS No: 160098-96-4 Molecular Formula: C₁₈H₁₅N₇O Solubility: H2O Primary Target: A2A Receptor Primary Target Ki: 600pM Storage and Stability: Store at 4°C under inert atmosphere. For maximum recovery of product, centrifuge the original vial prior to removing the cap.