217101
VLA-4 (CD49d)
Size
£889.00
- SKU:
- 217101
- Purity:
- Purified by Protein G affinity chromatography from culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Mouse spontaneous T lymphoma line TK1
- Clone:
- 14L1001
- Format:
- Supplied as a lyophilized powder in PBS. No preservative added. Reconstitute with sterile PBS.
- Extra Details:
- CD49d is a 150kD glycoprotein, also known as a4 integrin or VLA-4 a chain. It is a member of the integrin family, expressed on T and B cells, monocytes, eosinophils, basophils, mast cells, thymocytes, NK cells, and dendritic cells. CD49d is a heterodimer expressed with either of two b chains, b1 (CD29) or b7, to form the VLA-4 (integrin a4b1) or LPAM-1 (integrin a4b7) complexes. CD49d plays a critical role in both adhesion and T cell costimulation. The primary ligands for CD49d are VCAM-1, MAdCAM-1, and fibronectin. Applications: Suitable for use in Flow Cytometry, Immunoprecipitation, Immunohistochemistry, and Depletion. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Endotoxin: <0.002EU/ug Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice