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216723

Interleukin 7 (IL-7)

Size

£704.00

SKU:
216723
Application:
WB
Purity:
Purified by Protein G affinity chromatography from culture supernatant.
Storage Conditions:
-20°C
Supplier:
United States Biological
Host:
Rat
Immunogen:
Recombinant protein corresponding to mouse IL-7.
Clone:
14L627
Format:
Supplied as a lyophilized powder in PBS. Reconstitute with 200ul sterile PBS.
Extra Details:
IL-7 is a cytokine important for B- and T-cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth- stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T-cell receptor beta (TCRB) during early T-cell development. This cytokine can be pro- duced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:100-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice