216621
IL10RB (Interleukin 10 Receptor beta, IL-10 R beta)
Size
£704.00
- SKU:
- 216621
- Purity:
- Purified by Protein G affinity chromatography from culture supernatant.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to human IL-10 R beta
- Clone:
- 14L525
- Format:
- Supplied as a lyophilized powder in PBS. Reconstitute with 200ul sterile PBS.
- Extra Details:
- IL-10 RB is an 80-85kD member of the type II cytokine receptor family of proteins. It is very widely expressed, and serves as a signal transducing accessory chain when complexed to the ligand-binding chains for IL-10, IL-22, IL-28A, IL-28B and IL-29 (plus IL-26 in human). Mature mouse IL-10 RB is a type I transmembrane protein that is 330aa in length. It contains a 201aa extracellular domain aa20-220 that possesses two fibronectin type III domains aa22-107 and 111-208. There is one alternate start site at Met20. Over aa21-220, mouse IL-10 RB shares 87% and 74% aa identity with rat and human IL-10 RB. Applications: Suitable for use in Neutralization and Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-2000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice