CD11b (Mac-1, alphaM integrin, Cr3, MO-1, C3bi Receptor)

Size

£889.00

SKU:: 216241
Application:: Flow Cytometry
Purity:: Purified by Protein G affinity chromatography from culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: Mouse CD11a+ T Cells
Clone:: AP-MAB0813
Format:: Supplied as a lyophilized powder in PBS. Reconstitute with sterile PBS.
Extra Details:: CD11b is a 170kD glycoprotein, also known as aM integrin, Mac-1 a subunit, Mol, CR3, or Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, NK cells, and some T and B cells. CD11b non-covalently associates with CD18 (b2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen. Applications: Suitable for use in blocking of CD11b mediated cell adhesion. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Endotoxin: <0.002EU/ug Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.