B7-H3 (CD276)

Size

£691.00

SKU:: 216146
Application:: WB
Purity:: Purified by Protein G affinity chromatography from culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Recombinant protein corresponding to human B7-H3
Clone:: 14L50
Format:: Supplied as a lyophilized powder in PBS. Reconstitute with 200ul sterile PBS.
Extra Details:: B7-H3 is a member of the B7 family of proteins, which are, type I transmembrane glycoproteins containing two extracellular Ig domains. By engaging their cognate receptors on T cells, B7 family proteins provide accessory signals to T cells during T cell activation, which can be either stimulatory or inhibitory. B7-H3 is widely expressed and has been shown to be involved in bone formation via osteoblasts, allograft rejection and anti tumor response. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.