215414
Orexin B (Orexin, Hypocretin, Hcrt, HCRT, OX, PPORX, PPOX, Hypocretin-2, Hcrt2)
Size
£735.00
- SKU:
- 215414
- Purity:
- Purified by immunoaffinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Chicken/Avian
- Immunogen:
- A peptide from the N-terminal of human Orexin B aa1-14. Cellular Localization: Endoplasmic reticulum; rough endoplasmic reticulum. Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses.
- Format:
- Supplied as a liquid in PBS, 0.02% sodium azide.
- Extra Details:
- Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Orexin-A binds to both OX1R and OX2R with a high affinity, whereas orexin-B binds only to OX2R with a similar high affinity. SIMILARITY: Belongs to the orexin family. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:2000-1:5000 as a detection antibody and 1:200-1:1000 as a coating antibody. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice