215190
TREM-2 (Triggering Receptor Expressed on Myeloid Cells 2, Trem2a, Trem2b, Trem2c) (Low Endotoxin)
Size
£971.00
- SKU:
- 215190
- Application:
- Flow Cytometry
- Purity:
- Purified by Protein G affinity chromatography from tissue culture supernatant. Endotoxin: <0.01EU/ug
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rat
- Immunogen:
- Mouse TREM-2 Fc fusion protein
- Clone:
- 78.18
- Format:
- Supplied as a liquid in PBS. No preservative added.
- Extra Details:
- Triggering receptor expressed on myeloid cells 2 (TREM-2), an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Stimulation of TREM-2 enhances multinucleated osteoclast formation in vitro. Applications: Suitable for use in Flow Cytometry and Functional Assays. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:25-1:200, 10ul labels 1x106 cells in 100ul. Optimal dilutions to be determined by the researcher. Hybridoma: YB-2/0 myeloma cell line with lymph node cells from immunized Fisher rats. Endotoxin: <0.01EU/ug Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice