TREM-2 (Triggering Receptor Expressed on Myeloid Cells 2, Trem2a, Trem2b, Trem2c)

Size

£576.00

SKU:: 215188
Application:: Flow Cytometry
Purity:: Purified by Protein G affinity chromatography from tissue culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rat
Immunogen:: Mouse TREM-2 Fc fusion protein
Clone:: 78.18
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Triggering receptor expressed on myeloid cells 2 (TREM-2) is an activating receptor of the Ig superfamily. TREM-2 forms a receptor signalling complex with DAP12 to trigger the activation of the immune response in macrophages and dendritic cells. It may be involved in chronic inflammation and may promote the production of constitutive rather than inflammatory chemokines and cytokines. TREM-2 may also have a functional role in osteoclast formation. Applications: Suitable for use in Flow Cytometry. Other applications have not tested. Recommended Dilution: Flow Cytometry: 1:25-1:200, 10ul labels 1x10e6 cells in 100ul. Optimal dilutions to be determined by the researcher. Hybridoma: YB-2/0 myeloma cell line with lymph node cells from immunized Fisher rats. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.