215114
SDF-1 Alpha, Recombinant, Human (Stromal-Cell Derived Factor-1, CXCL12, PBSF)
Size
£544.00
- SKU:
- 215114
- Molecular Weight:
- 8
- Purity:
- ≥98% (SDS-PAGE, HPLC). Endotoxin: <0.1ng/ug
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a lyophilized powder. No preservative added. Reconstitute with 100ul sterile ddH2O.
- Extra Details:
- SDF-1α and β are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1α and β contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1α protein is the result of alternative splicing of the SDF-1 gene and contains 68 amino acid residues. Recombinant human SDF-1α is an 8kD protein containing 68 amino acid residues. Molecular Weight: ~8kD Amino Acid Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK Biological Activity: Determined by its ability to chemoattract IL-2-activated human T cells using a concentration range of 20-80ng/ml. Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice