Prolactin, Recombinant, Human (Luteotropic Hormone, PRL)

Size

£332.00

SKU:: 215097
Molecular Weight:: 23
Purity:: ≥98% (SDS-PAGE gel and HPLC). Endotoxin: ≤1EU/ug
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder. No preservative added. Reconstitute with sterile dH2O to 0.1-1mg/ml.
Extra Details:: Prolactin (PRL), also known as luteotropic hormone (LTH), is a neuroendocrine hormone and member of the somatotropin/prolactin family, which is secreted by the anterior pituitary, under the regulation of neuroendocrine neurons in the hypothalamus. The primary function of prolactin is the stimulation of breast development, and promotion of lactation during pregnancy and suckling, but prolactin also exhibits a weak luteotropic effect. Elevated levels of prolactin can be associated with hypothalamic disease, hypothyroidism, kidney disease, chest wall trauma or irritation, and tumors of the pituitary, including prolactinomas. Recombinant human Prolactin is a 23kD globular protein containing 200 amino acid residues. Molecular Weight: ~23kD (200aa residues) Biological Activity: Determined by its ability to induce the proliferation of rat Nb2-11 cells in the concentration range of 0.1-1.0ng/ml. Amino Acid Sequence: MLPICPGGAA RCQVTLRDLF DRAVVLSHYI HNLSSEMFSE FDKRYTHGRG FITKAINSCH TSSLATPEDK EQAQQMNQKD FLSLIVSILR SWNEPLYHLV TEVRGMQEAP EAILSKAVEI EEQTKRLLEG MELIVSQVHP ETKENEIYPV WSGLPSLQMA DEESRLSAYY NLLHCLRRDS HKIDNYLKLL KCRIIHNNNC Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice