215062
p63, CT (Tumor Protein p63, KET, P63, P73H, P73l, P73L, Tp73l, TP73L, Trp63)
Size
£704.00
- SKU:
- 215062
- Purity:
- Purified by affinity chromatography.
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide, C-NFDMDARRNKQQRIKEEGE, corresponding to aa662-680 within the C-terminal region of human p63.
- Format:
- Supplied as a liquid in PBS, 0.1% BSA, 0.09% sodium azide.
- Extra Details:
- Tumor protein p63, otherwise known as Tumor protein p73-like (p73L), is a widely expressed nuclear protein and homologue of tumor suppressor p53, which acts as a sequence-specific DNA binding transcriptional activator/repressor. p63, vital for the development of the prostate and selectively expressed by normal prostate basal cells, has been shown to be a promising complementary basal cell specific marker to High Molecular Weight-Cytokeratin (HMW-CK), for the differential diagnosis of benign prostatic lesions and prostatic carcinoma. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilutions: ELISA: 1:25,000 Western Blot: 1:250, detects a band of ~75kD in mouse lung and human tumor cell line K562 Immunohistochemistry (paraffin): 1:75 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice