IRGM, ID (Immunity-related GTPase Family M Protein, Immunity-related GTPase Family M Protein 1, Interferon-inducible Protein 1, LPS-stimulated RAW 264.7 Macrophage Protein 47 Homolog, LRG-47, IFI1, IRGM1, LRG47)

Size

£655.00

SKU:: 214960
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 14aa from near the internal region of human IRGM.
Format:: Supplied as a liquid in PBS, 0.02% sodium azide.
Extra Details:: IRGM is a putative GTPase required for clearance of bacterial and protozoan infections. It funtions in the innate immune response, most likely through regulation of autophagy. IRGM may also function in the regulation of proinflammatory cytokine production and in macrophage adhesion and motility. Applications: Suitable for use in ELISA, Western Blot, Immunohistochemistry and Immunofluorescence. Other applications not tested. Recommended Dilution: Western Blot: 1-2ug/ml, detects a band of ~32kD in human brain cell lysate. Immunohistochemistry (Paraffin): 5ug/ml Immunofluorescence: 20ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.