214960-BIOTIN

IRGM, ID (Immunity-related GTPase Family M Protein, Immunity-related GTPase Family M Protein 1, Interferon-inducible Protein 1, LPS-stimulated RAW 264.7 Macrophage Protein 47 Homolog, LRG-47, IFI1, IRGM1, LRG47) (Biotin)

Size

£869.00

SKU:: 214960-BIOTIN
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 14aa from near the internal region of human IRGM.
Format:: Supplied as a liquid in PBS, pH 7.2. Labeled with Biotin.
Extra Details:: IRGM is a putative GTPase required for clearance of bacterial and protozoan infections. It funtions in the innate immune response, most likely through regulation of autophagy. IRGM may also function in the regulation of proinflammatory cytokine production and in macrophage adhesion and motility. Detects a band of ~32kD in human brain cell lysate. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence. Other applications not tested. Recommended Dilution: Western Blot: detects a band of ~32kD in human brain cell lysate. Immunohistochemistry: paraffin Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.