Interleukin-15, Recombinant, Mouse (IL-15)

Size

£544.00

SKU:: 214932
Molecular Weight:: 13.3
Purity:: ≥98% (SDS-PAGE, HPLC). Endotoxin: ≤0.1ng/ug (<1EU/ug)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder in PBS. No preservative added. Reconstitute with sterile ddH2O to 0.1-1mg/ml. For extended storage the addition of 0.1% BSA is recommended.
Extra Details:: IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activities primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been linked to rheumatoid arthritis, inflammatory bowel disease, and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant mouse IL-15 is a 13.3kD protein consisting of 115 amino acid residues. Recombinant protein corresponding to mouse Interleukin-15 expressed in E. coli Molecular Weight: ~13.3kD (115aa) Biological Activity: The ED50 was determined by the stimulation of the proliferation of murine CTLL-2 cells is ≤ 5ng/ml, corresponding to a specific activity of ≥ 2x10e5 units/mg. Amino Acid Sequence: MNWIDVRYDL EKIESLIQSI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VAESGCKECE ELEEKTFTEF LQSFIRIVQM FINTS Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Shipping Conditions:: Blue Ice