214906
I-TAC (ITAC, SCYB11, SCYB9B, Interferon-inducible T-cell alpha Chemoattractant, CXCL11)
Size
£735.00
- SKU:
- 214906
- Purity:
- Purified by immunoaffinity chromatography. Endotoxin: ≤1EU/ug (LAL).
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Rabbit
- Immunogen:
- Recombinant protein corresponding to human I-TAC, expressed in E. coli.
- Format:
- Supplied as a lyophilized powder in PBS. No preservative added. Reconstitute with 100ul sterile ddH2O. For long term storage the addition of 0.09% sodium azide is recommended.
- Extra Details:
- I-TAC is a member of the CXC chemokine family, which signals through binding to CD183 (CXCR3), and is regulated by interferon gamma and beta. I-TAC is highly expressed by peripheral blood leucocytes, the pancreas and liver, and acts as a potent chemoattractant for IL-2 activated T cells, as well as a natural antagonist for CD195 (CCR5). Applications: Suitable for use in ELISA, Western Blot and Neutralization. Other applications not tested. Recommended Dilution: ELISA: 0.5-2ug/ml Western Blot: 0.1-0.2ug/ml Neutralization: To yield one-half maximal inhibition-[ND50]-of the biological activity of Human I‑TAC (100ng/ml), a concentration of 7.0-8.0ug/ml of this antibody is required. Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice