CD80 (B7-1) (FITC)

Size

£800.00

SKU:: 214746
Application:: Flow Cytometry
Purity:: Purified by affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: HTLV-1 transformed Lewis-S1 cells.
Clone:: 3H5
Format:: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Extra Details:: CD80, otherwise known as B7-1, is a type I transmembrane glycoprotein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells. CD80 is a B cell activation antigen, which functions in the CD28-CD80/CD86 co-stimulatory pathway vital for T cell activation and proliferation. In contrast, the interaction of CD80 with CD152 has an inhibitory effect on T cell responses. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.