CD71 (Transferrin Receptor, TfR)

Size

£570.00

SKU:: 214723
Purity:: Purified by Protein A affinity chromatography from tissue culture supernatant.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: KG1 cell line
Clone:: DF1513
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: CD71 cell surface antigen is a ~190kD homodimeric glycoprotein expressed by proliferating cells. CD71 is also known as the transferrin receptor. Mutation of the TFRC gene has been implicated in the development of Immunodeficiency 46 (IMD46) a combined immunodeficiency characterized by early onset chronic diarrhea, recurrent infections and intermittent neutropenia and thrombocytopenia (Jabara et al. 2016) Applications: Suitable for use in Immunofluorescence and Flow Cytometry. Not suitable for use Immunohistochemistry (paraffin or frozen sections). Other applications not tested. Recommended Dilution: Flow Cytometry: 1:10-1:25, 10ul labels 10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Hybridoma: NS1 myeloma cells with spleen cells from Balb/c mice. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.