CD205 (DEC-205)

Size

£639.00

SKU:: 214606
Application:: Flow Cytometry
Purity:: Purified by affinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Mouse
Immunogen:: Purified extracellular domain of human CD205-IgG1 Fc fusion protein. Species Sequence Homology: African Green, Baboon, Cynomolgus and Rhesus
Clone:: HD30
Format:: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Extra Details:: CD205 is a 210kD C-type lectin transmembrane protein, known as DEC-205. It belongs to macrophage mannose receptor family and is found at high levels on dendritic cells and thymic epithelial cells. Unlike murine CD205, human CD205 is also expressed at low levels on T- and B-cells, NK cells and monocytes. CD205, serves as an endocytic receptor, functions in antigen uptake/processing and clearance of apoptotic cells. Applications: Suitable for use in Flow Cytometry. Western Blot and Immunohistochemistry although not tested, have been reported in literature (ref. 1). Other applications not tested. Recommended Dilution: Flow Cytometry: ≤2ug/10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.