208735
Alpha 1-Acid Glycoprotein, Bovine (A1-AGP, A1AGP, Orosomucoid, ORM1, ORM Glycoprotein, Alpha-1-Acid, Of Serum alpha-1-Acid Glycoprotein alpha-1-AGP, AGP1)
Size
£639.00
- SKU:
- 208735
- Molecular Weight:
- 50
- Purity:
- Highly Purified (~99%)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a liquid in PBS, pH 7.4. No preservative added.
- Extra Details:
- A1AG serum protein, also called orosomucoid, is a monomer about 210aa residues long; the amino acid sequence has been determined through 192aa. A1AG is found in feline plasma in concentrations of 55-140mg per 100ml. It is a classical standard glycoprotein (40kD, ~40% carbohydrates) for studies on the structure of the oligosaccharide units. Its biological significance is unknown, although it can bind progesterone 15x as strongly as albumin. Sialic- acid-deficient alpha-1-AG has an affinity for vitamin B-12. Clinically, alpha 1 acid glycoprotein is an acute-phase reactant that together with haptoglobin is an indicator of acute inflammation. The alpha 1 acid glycoprotein:haptolobin ratio is useful in studies of bone marrow disorders, hemolytic processes and metastases. It is a positive acute phase reactant, the levels of which increase significantly in cats in response to inflammation, tissue injury and disease. A1AGP is purified using a combination of acid extraction, precipitation, gel filtration and affinity chromatography steps. Source: A1-AGP, from bovine plasma Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice