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208663

IL-7, Recombinant, Human, Animal Free (Lymphopoietin, 1LP-1, Pre-B Cell Factor)

Size

£351.00

SKU:
208663
Molecular Weight:
5.8
Purity:
≥98% (SDS-PAGE, HPLC) Endotoxin: ≤0.1ng/ug of protein (≤1EU/ug)
Storage Conditions:
-20°C
Supplier:
United States Biological
CAS Number:
11070-73-8
Format:
Supplied as a lyophilized powder. No additives. Reconstitute with ddH2O. Do not vortex.
Extra Details:
IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant human IL-7 is a 17.4kD protein containing 153aa residues. Manufactured using all non-animal reagents. Recombinant protein corresponding to human IL-7 expressed in E. coli. Biological Activity: Determined by its ability to stimulate the proliferation of mouse 2E8 cells. The expected ED50 is ≤0.5ng/ml, corresponding to a specific activity of ≥2x1e6units/mg. Amino Acid Sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH Related Substances: ≤0.2% Loss on Drying: ≤5% Storage and Stability: Lyophilized and reconstituted products are stable for 6 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Shipping Conditions:
Blue Ice