208529

DLL3, Recombinant, Human (Delta-like Protein 3, Delta3, Drosophila Delta Homolog 3)

Size

£448.00

SKU:: 208529
Molecular Weight:: 52
Purity:: ≥95% (SDS-PAGE). Endotoxin: <0.01EU/ug (LAL test; Lonza).
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder in PBS. Reconstitute with 100ul sterile ddH2O.
Extra Details:: DLL3 (Delta-like protein 3; Delta3) inhibits primary neurogenesis. It plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. DLL3 binds and activates Notch-1 or another Notch receptor. Defects in DLL3 are the cause of spondylocostal dysostosis type 1 (SCDO1). Recombinant protein corresponding to the extracellular domain of human DLL3 (aa27-466), fused at the N-terminus to a FLAG-Tag, expressed in HEK 293 cells. Molecular Weight: ~52kD (SDS-PAGE) Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.