ZIC2 (Zic family member 2 (odd-paired homolog, Drosophila), HPE5, Zic family member 2 (odd-paired Drosophila homolog), Zinc finger protein of the cerebellum 2, Zinc finger protein ZIC 2)

Size

£642.00

SKU:: 208513
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-HSGLSSNFNEWY, from the C-terminus of the protein sequence according to NP_009060.2. Species sequence homology: mouse, rat, canine and bovine
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: Zinc finger protein ZIC2 is a member of the GLI C2H2-type zinc-finger protein family. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Gene mutations cause holoprosencephaly type 5 in human brain and neural tube defects. Recent studies show that complete deficiency of the related murine ZIC2 transcription factor can also be a contributing factor to variable midline deficiencies, presenting during mid-gastrulation and similar forebrain anomalies. Applications: Suitable for use in Peptide ELISA and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:1000 Western Blot: 0.5-2ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.