HA-1 (aa57-71) (HMHA1, Histocompatibility (minor) HA-1, HLA-HA1, KIAA0223, Minor Histocompatibility antigen HA-1, Minor Histocompatibility protein HA-1)

Size

£642.00

SKU:: 208186
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to aa57-71 from sequence KATGTLKRPTSLSRH-C, at the N-terminus of the protein sequence according to NP_036424.2. Species sequence homology: human, mouse, rat and bovine
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: The minor histocompatibility antigen (mHags), HA-1 is a immunogenic alloantigen shown to be responsible for graft-versus-host disease (GVHD) in HLA-identical bone marrow transplantation. The antigen has two known alleles resulting in a single aa polymorphism. The HA-1H allele encodes histidine, whereas the HA-1R allele encodes arginine. Applications: Suitable for use in Peptide ELISA and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:128,000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.