208063

CDK10 (Cyclin-dependent Kinase 10, PISSLRE, CDC2-related Protein Kinase, Cell Division Protein Kinase 10, Cyclin-dependent Kinase (CDC2-like) 10, Cyclin-dependent Kinase Related Protein, Serine/Threonine Protein Kinase PISSLRE)

Size

£642.00

SKU:: 208063
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to AEPDLECEQIRLK, from the N-terminus of the protein sequence according to NP_443714.3.
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: Cdk10 (cell division protein kinase 10), otherwise known as PISSLRE, a Cdc2related kinase and member of the CMGC Ser/Thr protein. kinase family, essential for cell cycle progression, in the G2M phase. Studies have shown that Cdk10 can control the development of tamoxifen resistance in hormone sensitive breast cancer, and is therefore an important determinant of patient resistance to endocrine therapies. Applications: Suitable for use in Peptide ELISA and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:64,000 Western Blot: 2-3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.