ATG4C (ATG4 autophagy related 4 homolog C (S. cerevisiae), APG4-C, APG4C, AUTL1, AUTL3, FLJ14867, APG4 autophagy 4 homolog C, AUT-like 1, Cysteine Endopeptidase, AUT-like 3 cysteine Endopeptidase, OTTHUMP00000010715, Autophagin-3, Autophagy-related cysteine Endopeptidase 3)

Size

£642.00

SKU:: 208013
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Goat
Immunogen:: Synthetic peptide corresponding to C-EDEKKQLKRFSTEE, from the C-terminus of the protein sequence according to NP_116241.2; NP_835739.1. Species sequence homology: bovine and canine
Format:: Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Extra Details:: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq]. Applications: Suitable for use in Peptide ELISA and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:16,000 Western Blot: 2-6ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Shipping Conditions:: Blue Ice