207685
GTF3A (Transcription Factor IIIA, General Transcription Factor IIIA, AP2, TFIIIA)
Size
£685.00
- SKU:
- 207685
- Purity:
- Purified
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Host:
- Mouse
- Immunogen:
- Recombinant protein corresponding to aa185-274 from human GTF3A with GST tag. MW of the GST tag alone is 26kD.
- Clone:
- 4B4
- Format:
- Supplied as a liquid in PBS, pH 7.4.
- Extra Details:
- The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. AA Sequence: NQQKQYICSFEDCKKTFKKHQQLKIHQCQNTNEPLFK CTQEGCGKHFASPSKLKRHAKAHEGYVCQKGCSFVA KTWTELLKHVRETHKEE Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
- Shipping Conditions:
- Blue Ice