Resiquimod (R-848, S 28463)

Size

£223.00

SKU:: 207380
Molecular Weight:: 314.4
Purity:: ≥98% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 144875-48-9
Format:: White to off-white powder
Extra Details:: Immune response modifier. Potent antitumor and antiviral compound. Stimulates antibody secretion and cytokine production. Used as adjuvant to increase the effectiveness of vaccines. Potent and selective synthetic ligand for Toll-like receptor 7 (TLR7) in mouse and for TLR7 and TLR8 in human. Activates immune cells via the TLR7/TLR8 MyD88-dependent signaling pathway and leads to the induction of NF-kappaB. NLRP3/NALP3 inflammasome activator, independent of TLRs and RIG-I. Upregulator of the opioid growth factor receptor. Used in the treatment of skin lesions such as herpes simplex virus. Synonyms: 1-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol; 4-Amino-2-(ethoxymethyl)-1-(2-hydroxyisobutyl)imidazo[4,5-c]quinoline; 4-Amino-2-ethoxymethyl-α,α-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol; R 848; Resiquimod; S 28463 CAS Number: 144875-48-9 Molecular Formula: C₁₇H₂₂N₄O₂ Molecular Weight: 314.4 Appearance: White to off-white powder Purity: ≥98% Solubility: Soluble in DMSO, dichloromethane or methanol. Slightly soluble in acetonitrile or ethyl acetate. Storage and Stability: Store at -20°C.. Stable for 12 months after receipt. Light sensitive.