207378

Rebeccamycin (NSC 359079, BRN 4732638)

Size

£351.00

SKU:: 207378
Molecular Weight:: 570.4
Purity:: ≥98% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 93908-02-2
Format:: Supplied as a yellow solid.
Extra Details:: Antibiotic. Weak topoisomerase I (Topo I) inhibitor. Structurally similar to staurosporine. Does not show any inhibitory activity against protein kinases. Shows significant antitumor properties in vitro (IC50=480nM against mouse B16 melanoma cells and IC50 =500nM against P388 leukemia cells). Does not show any inhibitory activity against protein kinases. Synonyms: NSC 359079; BRN 4732638, 1,11-dichloro-12,13-dihydro-12-(4-O-methyl-β-D-glucopyranosyl)-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione CAS Mo: 93908-02-2 Source: Streptomyces sp. Molecular Formula: C₂₇H₂₁Cl₂N₃O₇ Molecular Weight: 570.4 Solubility: DMSO Method for Determining Identity: Proton NMR Purity: ≥98% (HPLC) Appearance: Supplied as a yellow solid. Storage and Stability: May be stored at 4°C for short-term only. Long-term storage is recommended at -20°C. Stable for 1 year after receipt. Protect from light when in solution. For maximum recovery of product, centrifuge the original vial prior to removing the cap.