207326

PARP2 (ARTD2, Poly(ADP-ribose) Polymerase 2, ADP-ribosyltransferase Diphtheria Toxin-like 2, NAD(+) ADP-ribosyltransferase 2)

Size

£466.00

SKU:: 207326
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Recombinant protein corresponding to aa1-207 from mouse PARP-2.
Format:: Supplied as a liquid in 0.09% sodium azide.
Extra Details:: PARP-2 (ARTD2) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. Applications: Suitable for use in Western Blot, Immunoprecipitation, Immunohistochemistry and Immunocytochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:2000-1:5000 Immunohistochemistry: 1:500-1:1000 Immunocytochemistry: 1:500-1:1000 Immunoprecipitation: 2ul/100ug nuclear extract Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.