207199
Ganglioside GD1b, Disodium Salt (GD1b•2Na)
Size
£418.00
- SKU:
- 207199
- Molecular Weight:
- 1836.146
- Purity:
- ~98% (TLC)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- CAS Number:
- 19553-76-5
- Format:
- White to off-white powder
- Extra Details:
- Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell interactions, tumorigenesis and metastasis. The accumulation of gan- gliosides has been linked to several diseases. Ganglioside GD1b may act as a bacterial toxin receptor (tetanus, botulinus). High levels are found in gliomas and astrocytomas. It modulates protein kinase activities. In vivo and in vitro it is in equilibrium with the lactone structure. Source: Bovine brain Synonyms: Ganglioside C1 Disodium Salt; GD1b Disodium Salt; GD1b Ganglioside Disodium Salt; Ganglioside G2 Disodium Salt; Ganglioside GIII Disodium Salt; II3Neu5Ac2GgOse4Cer;b-Gal-(1-3)-b-GalNAc-(1-4)-[a-Neu5Ac-(2-8)-a-Neu5Ac-(2-3)-]b-Gal-(1-4)-b-Glc-(1-1)-Cer; GD1b•2Na; Disialoganglioside GD1b•2Na Molecular Formula: C84H146N4O39•2Na Molecular Weight: ~1836.1, 46.0 (calculated on sphingosine C18:1 and stearic acid) Appearance: White to off-white powder Purity: ~98% (TLC) Solubility: Reconstitute in water (micellar aggregates) or Chloroform:Methanol (2:1). Storage and Stability: Powder may be stored at -20°C. Stable for 6 months after receipt at -20°C.
- Shipping Conditions:
- Blue Ice