207187

FNDC5, Recombinant (Fibronectin Type III Domain-containing Protein 5, Fibronectin Type III Repeat-containing Protein 2, FRCP2, Irisin)

Size

£362.00

SKU:: 207187
Molecular Weight:: 16
Purity:: ~95% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder in PBS. Reconstitute with 100ul sterile dH2O.
Extra Details:: Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure. Source: Recombinant protein corresponding to the extracellualar domain of human FNDC5 (aa32-152)/mouse (aa29-149), untagged, expressed in E. coli. Molecular Weight: ~16kD Endotoxin: <0.01EU/ug purified protein (LAL test; Lonza) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.