207178
FGF-1, Recombinant, Mouse, aa16-155 (Fibroblast Growth Factor 1, Acidic Fibroblast Growth Factor, Endothelial Cell Growth Factor, ECGF, Heparin-binding Growth Factor 1, HBGF-1)
Size
£301.00
- SKU:
- 207178
- Molecular Weight:
- 16
- Purity:
- ≥95% (SDS-PAGE)
- Storage Conditions:
- -20°C
- Supplier:
- United States Biological
- Format:
- Supplied as a lyophilized powder in PBS, 0.2mM DTT. Reconstitute with 100ul sterile dH2O.
- Extra Details:
- Fibroblast growth factors (FGFs) constitute a family of heparin-binding polypeptides involved in the regulation of biological responses such as growth, differentiation and angiogenesis. The biological effects of FGFs are mediated by four structurally related receptor tyrosine kinases denoted FGFR1, FGFR2, FGFR3 and FGFR4. FGF-1 [FGF-acidic; ECGF; HBGF-1] is a powerful mitogen of cells of mesodermal, ectodermal and endodermal origin. FGF-1 association with heparan sulfate is a prerequisite for activation of FGF receptors. FGF-1 plays a role in various stages of development and morphogenesis as well as in angiogenesis and wound healing processes. Recent data indicate a role of FGF-1 in inflammation and obesity. FGF-1 is selectively induced in fat cells by high-fat diet feeding and established the PPARgamma-FGF-1 axis as a critical pathway that regulates adipose tissue remodeling. Source: Recombinant protein corresponding to aa16-155 from mouse FGF-1, untagged, expressed in E. coli. Molecular Weight: ~16kD Endotoxin: <0.01EU/ug (LAL) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
- Shipping Conditions:
- Blue Ice