207104

CD160, Recombinant, Human, aa27-159 (Natural Killer Cell Receptor BY55, NK28, NK1)

Size

£576.00

SKU:: 207104
Purity:: ~98% (SDS-PAGE)
Storage Conditions:: -20°C
Supplier:: United States Biological
Format:: Supplied as a lyophilized powder in PBS. Reconstitute with sterile PBS to 100ug/ml.
Extra Details:: CD160 is a GPI-anchored lymphocyte surface receptor in which expression is mostly restricted to the highly cytotoxic CD56(dim) CD16(+) peripheral blood NK subset. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules. CD160 acts as a co-activator receptor for CD3-induced proliferation of CD4+ CD160+ T cells isolated from inflammatory skin lesions. CD160-Fc fusion protein targets a novel costimulatory pathway and prolongs allograft survival. Source: Recombinant protein corresponding to aa27-159 from human CD60, fused to the N-terminus of the Fc region of human IgG1, expressed in CHO cells. Biological Activity: Measured by its binding ability in a functional ELISA. Endotoxin: ~0.06EU/ug protein (LAL test; Lonza) Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.