207085

Bafilomycin C1 (L-681,110A1, 2-Demethyl-2-methoxy-24-methyl-hygrolidin)

Size

£435.00

SKU:: 207085
Molecular Weight:: 720.9
Purity:: ≥98% (HPLC)
Storage Conditions:: -20°C
Supplier:: United States Biological
CAS Number:: 88979-61-7
Format:: Supplied as a yellow powder.
Extra Details:: Antibiotic. Specific vacuolar-type H+-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antibacterial, antifungal, insecticidal and antihelmintic. Potential anti-osteoporotic agent in treating bone lytic diseases. Neuroprotection inducer. CAS Number: 88979-61-7 Source: Streptomyces sp. Gö 14F Formula: C39H60O12 Method for Determining Identity: Proton NMR Solubility: 100% ethanol, methanol, DMSO or dimethyl formamide. May undergo transformation to methyl ketal on long term storage in methanol. Recommend the use of fresh solutions. Molecular Weight: ~720.9 Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile buffer or ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.