171951

PD-1, Recombinant, Human (Programmed cell death 1, PDCD1, SLEB2, CD279, HPD-L) (Biotin)

Size

£900.00

SKU:: 171951
Molecular Weight:: 44.5
Purity:: As Reported
Storage Conditions:: -70°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 8mM phosphate, pH 7.4 110mM NaCl, 2.2mM KCl, 20% glycerol. Labeled with Biotin.
Extra Details:: Human secreted programmed cell death 1 (PD-1)-Fc fusion protein, also known as, PDCD1, SLEB2, CD279 and HPD-L, GenBank Accession No. NM_005018, a.a25-167, with C-terminal expressed in a HEK293 cell expression system and enzymatically biotin-labeled. MW = 44.5kD. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation. Source: Recombinant protein corresponding to aa25-167 from PD-1 at C-terminus, expressed in a HEK293 cell expression system. Molecular Weight: ~44.5kD Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectively profiling. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap Amino Acid Sequence: (25)LDSPDRPWNPPTFSPALLVVTEGDNATFTCSFSNTSESFVLNWYRMSPSNQTDKLAA FPEDRSQPGQDCRFRVTQLPNGRDFHMSVVRARRNDSGTYLCGAISLAPKAQIKESL RAELRVTERRAEVPTAHPSPSPRPAGQFQ (167) IEGRMD (linker) (100)PKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGVFSCSVMHEALHNHYTQKSLSLSPGK (330) Fc of human IgG1 GGGLNDIFEAQKIEWHE (Avi-tagTM)

Shipping Conditions:: Dry Ice