171925

MMP9 (Q279R), Recombinant, Human (Matrix metallopeptidase-9, gelatinase B, MANDP2, CLG4B, Macrophage gelatinase, GELB, EC 3.4.24)

Size

£1,002.00

SKU:: 171925
Molecular Weight:: 77.8
Purity:: ≥90%
Storage Conditions:: -70°C
Supplier:: United States Biological
Format:: Supplied as a liquid in 40mM Tris-HCl, pH 8.0, 110mM sodium chloride, 2.2mM potassium chloride, 200mM imidazole, 20% glycerol.
Extra Details:: The MMP-9 Q279R variant has been found in patients with polycythemia vera, essential thrombocytosis, or idiopathic myelofibrosis. Recombinant protein corresponding to aa20-707 of MMP9, with Gln to Arg mutation on amino acid 279, fused to His-Tag at the C-terminus, expressed in an HEK293 cell expression system. Molecular Weight: ~77.8kD Specific Activity: 2500pmole/min/ug Application: Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap