WNT10B (Protein Wnt-10b, SHFM6, WNT-12, WNT-10B Protein, WNT12, Protein Wnt-12)

Size

£709.00

SKU:: 171418
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 16aa from the internal region of human WNT10B. Species sequence homology: hamster.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Wnt genes encode a family of secreted proteins having oncogenic potential and important roles in developmental processes. WNT10B has been implicated in several cancers, including breast cancer and gastric cancer. WNT10B expression has been shown to be modulated by IFNgamma, TNFalpha, retionic acid, and beta estradiol. WNT10B might be implicated in self renewal of stem cells as well as in carcinogenesis through activation of the WNT-beta-catenin pathway. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 10-15ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.