MUPCDH (CDHR5, Mu-protocadherin, Mucin and cadherin-like, Mucin-like protocadherin, MU-PCDH, MUCDHL, MUCDHL-ALT, MUCDHL-FL)

Size

£709.00

SKU:: 170988
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 17aa from the internal region of human MUPCDH. Species sequence homology: monkey.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: Mucin-like protocadherin is a developmentally regulated cell adhesion molecule that contains an extracellular region with four cadherin-like ectodomains and a triply repeating mucin domain in its' longer isoform. This later domain is known to negatively regulate cadherin function in carcinoma cells. During development, MUCDHL functions in the generation of the three-dimensional structure of the kidney. In adult kidney it is localized to the brush border of the proximal convoluted tubule. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 10ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.