LOXL2 (Lysyl oxidase-like Protein 2, Lysyl oxidase Related 2, Lysyl Oxidase-like 2, WS9-14, LOR2, Lysyl Oxidase Homolog 2)

Size

£709.00

SKU:: 170914
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 20aa from the internal region of human LOXL2. Species sequence homology: bat.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: LOXL2 is a member of the lysyl oxidase gene family. This family of extracellular, copper dependent enzymes participates in the post-translational modification essential to the biogenesis of connective tissue by deaminating the side chains of lysine residues in collagen and elastin. This results in the covalent cross-linking of fibrillar collagen and the formation of desmosine and isodesmosine cross-links in elastin. Members of the lysyl oxidase family play a role in tumor suppression, cell adhesion and senescence. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 15ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.