G-Protein-Coupled Receptor 54 (KISS1R, AXOR12, GPR54, HOT7T175, KISS-1R, KISS1 Receptor, G-Protein-Coupled Receptor 54, Metastin Receptor, Rot7t175, G-Protein Coupled Receptor 54, HH8, Hypogonadotropin-1, KiSS-1 Receptor, Kisspeptins Receptor)

Size

£646.00

SKU:: 170537
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 20aa from the C-terminus of human G protein-coupled receptor 54. Species sequence homology: gibbon and monkey.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: G protein-coupled receptor 54 is a Metastin Receptor. Metastin, also known as KiSS-1, is a metastasis suppressor gene. Mutations in GPR54 have been shown to cause autosomal recessive idiopathic hypogonadotropic hypogonadism in humans and mice, suggesting that GPR54 is a key regulator for the onset of puberty (Seminara et al. 2003). Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 3-5ug/ml Requires HIER using sodium citrate buffer pH6.0 prior to staining. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.