FZD5 (FZD5, C2orf31, DKFZP434E2135, Frizzled Family Receptor 5, Fz5, Fzd-5, FzE5, Frizzled 5, Frizzled-5, Wnt Receptor, Fz-5, HFZ5)

Size

£735.00

SKU:: 170514
Application:: IHC-Fr
Purity:: Purified by immunoaffinity chromatography.
Storage Conditions:: -20°C
Supplier:: United States Biological
Host:: Rabbit
Immunogen:: Synthetic peptide corresponding to 16aa from 3rd cytoplasmic domain of human FZD5/Frizzled 5. Species sequence homology: gibbon, monkey, mouse, rat, bovine, canine, porcine and rabbit.
Format:: Supplied as a liquid in PBS, 0.09% sodium azide.
Extra Details:: FZD5 is a Frizzled Receptor that mediates Wnt signaling. FZD5 is associated with limb bud and bone marrow stem cell development. FZD5 contributes to the activated state of fibroblast-like synoviocytes from patients with rheumatoid arthritis. Recently, FZD5 has been implicated in melanoma metastasis through the Wnt5a and PKC pathway. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 24ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.